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Flexeril, Yurelax (Cyclobenzaprine) additional information

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Common uses of Flexeril, Yurelax, cyclobenzaprine

Cyclobenzaprine is indicated as an adjunct to rest and physical therapy for relief of muscle spasm associated with acute, painful musculoskeletal conditions.

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Cyclobenzaprine comes as a capsule, 10 mg., to take by mouth.

The usual dosage of cyclobenzaprine is 10 mg 3 times a day, with a range of 20 to 40 mg a day in divided doses. Dosage should not exceed 60 mg in any 24 hours.

Cyclobenzaprine has not been found effective in the treatment of spasticity associated with cerebral or spinal cord disease, or in children with cerebral palsy.

If you miss a dose, take it as soon as remembered if it is within an hour or so. If you do not remember until later, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.


Cyclobenzaprine should be used only for short periods (up to two or three weeks) because evidence of effectiveness for more prolonged use is not available and because muscle spasm associated with acute, painful musculoskeletal conditions is generally of short duration and specific therapy for longer periods is seldom warranted.

Cyclobenzaprine may interact with monoamine oxidase (MAO) inhibitors. Hyperpyretic crisis, severe convulsions, and deaths have occurred in patients receiving tricyclic antidepressants and MAO inhibitor drugs.

Cyclobenzaprine may enhance the effects of alcohol, barbiturates, and other CNS depressants.

Cyclobenzaprine may impair the mental and/or physical abilities needed for certain potentially hazardous activities such as driving a car or operating machinery.

Cyclobenzaprine should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether cyclobenzaprine is excreted in human milk. Because cyclobenzaprine is closely related to the tricyclic antidepressants, some of which are known to be excreted in human milk, caution should be exercised when cyclobenzaprine is administered to a nursing woman. Consult your doctor before breast-feeding.

Because of its atropine-like action, cyclobenzaprine should be used with caution by individuals with a history of urinary retention, angle-closure glaucoma, increased intraocular pressure, and by individuals taking anticholinergic medication.

Safety and effectiveness of cyclobenzaprine in pediatric patients below 15 years of age have not been established.

Possible side effects

The most frequently observed side effects of cyclobenzaprine are drowsiness, dry mouth, and dizziness.

Less frequent side effects include fatigue/tiredness, asthenia, nausea, constipation, dyspepsia, unpleasant taste, blurred vision, headache, nervousness and confusion.

If you notice other effects not listed above, contact your doctor.


If overdose of cyclobenzaprine is suspected, contact your local poison control center or emergency room immediately. High doses of cyclobenzaprine may cause temporary confusion, disturbed concentration, transient visual hallucinations, agitation, hyperactive reflexes, muscle rigidity, vomiting, or hyperpyrexia. Overdosage may cause drowsiness, hypothermia, tachycardia and other cardiac rhythm abnormalities. Other manifestations may be dilated pupils, convulsions, severe hypotension, stupor and coma.

Additional information

Keep cyclobenzaprine (Flexeril, Yurelax) in a tightly closed container and out of reach of children. Store cyclobenzaprine at room temperature and away from excess heat and moisture (not in the bathroom).


The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, or other healthcare professional. It should not be construed to indicate that use of cyclobenzaprine (Flexeril, Yurelax) is safe, appropriate, or effective for you. Consult your health care professional before you buy Flexeril, Yurelax (Cyclobenzaprine).

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