Codeine phosphate, obtained from opium or prepared from morphine by methylation, is a centrally acting analgesic used for the relief of mild to moderately severe pain.
Codeine is used as an analgesic, a cough suppressant or as an anti-diarrheal agent. The phosphate of the alkaloid codeine is used because of its free solubility in water.
COD-Efferalgan with codeine and paracetamol, combines the analgesic effects of a centrally acting analgesic, codeine, with a peripherally acting analgesic, paracetamol. Codeine and paracetamol is used for the relief of mild to moderately severe pain.
COD-Efferalgan comes as an effervescent tablet containing 30 mg. codeine and 500 mg. paracetamol, usually taken every 12 hours or as needed.
Codeine can be habit-forming. Do not take a larger dose, more often, or for a longer period than your doctor tells you to.
If you miss a dose, take it as soon as remembered if it is within an hour or so. If you do not remember until later, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.
Before taking codeine and paracetamol, tell your doctor if you are allergic to codeine, paracetamol, sulfite or any other drugs.
Tell your doctor what prescription and nonprescription medications you are taking, especially other pain relievers, anticoagulants, antidepressants, corticosteroids, MAO inhibitors, medications for cough, cold, or allergies, medications for diabetes, arthritis, or gout, sedatives, sleeping pills, tranquilizers and vitamins.
Tell your doctor if you have or have ever had a bleeding disorder, ulcer disease, liver or kidney disease, a history of alcoholism, anemia, lung or thyroid disease, prostatic hypertrophy, or urinary problems.
Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking codeine and paracetamol, call your doctor.
If you are having surgery, including dental surgery, tell the doctor or dentist that you are taking codeine and paracetamol.
Codeine may make you drowsy. Do not drive a car or operate machinery until you know how codeine affects you.
Alcohol can add to the drowsiness caused by codeine.
Possible side effects
Although side effects from codeine and paracetamol are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away: dizziness, lightheadedness, drowsiness, upset stomach, vomiting, constipation, stomach pain, difficulty urinating.
If you experience any of the following symptoms, call your doctor immediately: difficulty breathing, rash or itching, ringing in the ears or decreased hearing, abnormal bruising or bleeding.
If overdose of codeine with paracetamol is suspected, contact your local poison control center or emergency room immediately.
Keep codeine with paracetamol in a tightly closed container and out of reach of children. Store codeine with paracetamol at room temperature and away from excess heat and moisture (not in the bathroom).
The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, or other healthcare professional. It should not be construed to indicate that use of codeine with paracetamol is safe, appropriate, or effective for you.
Consult your health care professional before you