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Disdolen Codeine additional information

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Common uses

Disdolen Codeine is a combination of fosfosal, an acetylsalicylic derivate, and codeine. Disdolen Codeine is often prescribed for muscle skeletal pain, joint pain, migraine, posttraumatic pain, postsurgical pain and menstrual pain.

Fosfosal has both an antiinflammatory and an analgesic effect. Fosfosal lacks the negative effect on ulcer and hemmorea, which is common in this type of medicine.

Codeine is used as a centrally acting analgesic for the relief of mild to moderately severe pain, a cough suppressant, or a sedative / hypnotic drug. The phosphate of the alkaloid codeine is used because of its free solubility in water.

Directions

Disdolen Codeine comes as an effeverscent powder to dissolve in water. Each bag contains 30 mg. codeine phosphate and 1200 mg. fosfosal.

Doses used to relief pain is one bag of Disdolen Codeine every four to six hours not to exceed three bags in any 24 hours.

If you miss a dose, take it as soon as remembered if it is within an hour or so. If you do not remember until later, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

Precautions

Codeine should not be used by individuals with hypersensitivity to opioid analgesics, acute asthma or other obstructive airway disease and acute respiratory depression, cor pulmonale, acute alcoholism, delirium tremens, severe CNS depression, convulsive disorders, increased cerebrospinal or intracranial pressure, head injury, suspected surgical abdomen, concomitant MAO inhibitors (or within 14 days of such therapy).

Codeine should be used with extreme caution in patients with substantially decreased respiratory reserve, pre-existing respiratory depression, hypoxia or hypercapnia.

Codeine administration may result in severe hypotension in individuals whose ability to maintain adequate blood pressure is compromised by reduced blood volume, or concurrent administration of such drugs as phenothiazines or certain anesthetics.

Codeine should be administered with caution, and in reduced dosages, to elderly or debilitated patients, to individuals with severely reduced hepatic or renal function, and in individuals with Addison's disease, hypothyroidism, prostatic hypertrophy or urethral stricture.

Codeine may impair the mental and/or physical abilities needed for certain potentially hazardous activities such as driving a car or operating machinery. Patients should be cautioned accordingly.

Codeine should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Codeine is excreted into breast milk. Consult your doctor before breast-feeding.

The analgesic effect of codeine is potentiated by amphetamines, chlorpromazine and methocarbamol. CNS depressants, such as other opioids, anesthetics, sedatives, hypnotics, barbiturates, phenothiazines, chloral hydrate and glutethimide may enhance the depressant effects of codeine. MAO inhibitors, pyrazolidone antihistamines, beta-blockers and alcohol may also enhance the depressant effect of codeine. When combined therapy is contemplated, the dose of one or both agents should be reduced.

Possible side effects

The most frequently observed side effects of opioid analgesics such as codeine are sedation, nausea and vomiting, constipation, lightheadedness, dizziness, and sweating.

Less frequent side effects include dysphoria, euphoria, weakness, headache, agitation, tremor, uncoordinated muscle movements, alterations of mood, muscle rigidity, paresthesia, muscle tremor, blurred vision, nystagmus, diplopia and miosis, transient hallucinations and disorientation, visual disturbances, insomnia and increased intracranial pressure may occur.

If you notice other effects not listed above, contact your doctor.

Overdose

If overdose of Disdolen Codeine is suspected, contact your local poison control center or emergency room immediately. Serious overdosage with opioids may be characterized by respiratory depression, extreme somnolence progressing to stupor or coma, skeletal muscle flaccidity, cold and clammy skin, and sometimes bradycardia and hypotension. In severe overdosage, apnea, circulatory collapse, cardiac arrest and death may occur

Additional information

Keep Disdolen Codeine in a tightly closed container and out of reach of children. Store Disdolen Codeine at room temperature and away from excess heat and moisture (not in the bathroom).

Physical dependence with or without psychological dependence tends to occur on chronic administration of opioids such as codeine. The following withdrawal symptoms may be observed after opioids are discontinued: body aches, diarrhea, gooseflesh, loss of appetite, nervousness or restlessness, runny nose, sneezing, tremors or shivering, stomach cramps, nausea, trouble with sleeping, unusual increase in sweating and yawning, weakness, tachycardia and unexplained fever. Individuals who are appropriately treated with opioid analgesics and who undergo gradual withdrawal from codeine, these symptoms are usually mild.

Note

The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, or other healthcare professional. It should not be construed to indicate that use of Disdolen Codeine is safe, appropriate, or effective for you.
Consult your health care professional before you buy Disdolen Codeine.

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